منابع مشابه
Harnessing Scientific Literature Reports for Pharmacovigilance
OBJECTIVES We seek to develop a prototype software analytical tool to augment FDA regulatory reviewers' capacity to harness scientific literature reports in PubMed/MEDLINE for pharmacovigilance and adverse drug event (ADE) safety signal detection. We also aim to gather feedback through usability testing to assess design, performance, and user satisfaction with the tool. METHODS A prototype, o...
متن کاملNetwork tomography from aggregate loss reports
Multicast applications and network monitors can potentially benefit from the ability to infer the loss rates along links within a multicast tree. Estimators, known generically by minc, or multicast inference of network characteristics, have been developed to provide this ability. They consider multicast data packets to be probes, and conduct inference based upon reports of which probes reached ...
متن کاملUterine perforation with the levonorgestrel-releasing intrauterine device: analysis of reports from four national pharmacovigilance centres.
BACKGROUND Levonorgestrel-releasing intrauterine devices (LNG-IUD) are commonly used for contraception and other indications in many countries. National pharmacovigilance centres have been receiving reports from healthcare professionals and patients of uterine perforation associated with the use of these LNG-IUDs. METHODS National pharmacovigilance centres in the Netherlands, New Zealand, Swi...
متن کاملPharmacovigilance analysis of adverse event reports for aliskiren hemifumarate, a first-in-class direct renin inhibitor
BACKGROUND The purpose of this study was to examine the postmarketing safety profile of aliskiren hemifumarate, a first-in-class direct renin inhibitor. METHODS The US Adverse Event Reporting System (AERS) was utilized to conduct a retrospective pharmacovigilance analysis by applying the Multi-item Gamma Poisson Shrinker data mining algorithm to calculate empiric Bayes geometric mean (EBGM) v...
متن کاملA Knowledge Management Platform for Documentation of Case Reports in Pharmacovigilance
Most countries have developed information systems to report drug adverse effects. However, as in other domains where systematic reviews are needed, there is little guidance on how systematic documentation of drug adverse effects should be performed. The objective of the VigiTermes project is to develop a platform to improve documentation of pharmacovigilance case reports for the pharmaceutical ...
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ژورنال
عنوان ژورنال: Journal of Pharmaceutical Research
سال: 2015
ISSN: 2454-8405,0973-7200
DOI: 10.18579/jpcrkc/2015/0/0/79781